As with any test, there may be false positives or false negatives. Pregnancy management decisions should not be based on the results of a cfDNA test alone. QNatal is a “screening” test, not a diagnostic test, and therefore all positive/increased risk results should be followed by genetic counseling and further diagnostic testing and procedures, when clinically indicated. QNatal Advanced is not recommended before 10 weeks gestation due to a significantly increased risk of a failed result. QNatal Advanced must not be used earlier than 10 weeks into pregnancy. This test does not assess the risk of fetal anomalies such as neural tube defects or ventral wall defects. In addition, if selected as an option, QNatal Advanced can screen for certain microdeletions (ie, 22q, 5p, 1p36, 15q, 11q, 8q, and 4p) that may cause birth defects, and/or for fetal sex. Quest Diagnostics, 2020.ī Alternative UPP pricing is available in Florida, New Hampshire, Massachusetts, Maine, Rhode Island, Vermont, and TexasĬ QNatal ® Advanced is a cell-free DNA test that screens for increased risk of certain fetal chromosomal abnormalities that may cause birth defects, including Trisomy 21 (Down Syndrome), Trisomy 18, Trisomy 13, and certain sex chromosome abnormalities (ie, 45,X, 47,XXY, 47,XXX, and 47,XYY).

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